Most visitor facilities within the preserve are open and accessible every day of the year. Some seasonal and emergency closures may occur.
Miami International Airport services the area from the east coast, Ft. Myers International Airport from the west coast.
I-75, state road 29, and U.S. 41 all travel through the preserve
There is no public transportation within the Preserve.
The preserve includes 31 miles of the Florida Trail which can be very wet in the rainy season. The Tree Snail Hammock Nature Trail is a short, self-guided trail located on Loop Road. Two scenic drives through the preserve provide leisurely wildlife viewing. The Loop Road is a 26-mile, single-lane, unimproved road beginning and ending on highway 41. Turner River Road and Birdon Road form a u-shaped, 17-mile graded-dirt drive.