Sequoia and Kings Canyon National Parks support a diversity of animal species. There are over 260 known native vertebrate species in the parks, and numerous additional species may be present. Of the native vertebrates, five species are extirpated, and over 150 are rare or uncommon.
While there have been some studies of park invertebrates, there is not enough information to know how many species occur in the parks. Many of the parks' caves contain invertebrates, some of which occur only in one cave and are known nowhere else in the world. The variety of wildlife in the parks reflects the variety in elevation, climate, and habitat.